Description
Compound:
Ambroxol
Compound:
Each 1 ml of solution contains:
Ambroxol hydrochloride 7.5 mg
Auxiliary components:
Glycerin, propylene glycol, 70% sorbitol, strawberry flavor, carmoisine, purified water.
Properties:
A mucolytic and expectorant agent, is an active N-demethylated metabolite of bromhexine. It has a secretomotor, secretolytic and expectorant effect. Stimulates serous cells of the bronchial mucosa, increases the motor activity of the ciliated epithelium by acting on type 2 pneumocytes in the alveoli and Clara cells in the bronchioles, enhances the formation of endogenous surfactant – a surface-active substance that ensures the sliding of bronchial secretions in the lumen of the respiratory tract.
Ambroxol increases the proportion of serous component in bronchial secretion, improving its structure and helping to reduce viscosity and liquefy sputum; as a result, mucociliary transport improves and sputum removal from the bronchial tree is facilitated.
When taking ambroxol orally, the effect, on average, occurs within 30 minutes and lasts 6-12 hours, depending on the single dose.
Indications:
Respiratory diseases accompanied by the release of viscous sputum and difficulty in expectorating sputum: acute and chronic bronchitis; pneumonia; bronchial asthma; bronchiectasis; COPD.
Method of administration and dosage:
The duration of treatment is determined by the doctor individually and depends on the severity of the disease. If it is necessary to use the drug for more than 4-5 days, a doctor’s consultation is required.
For oral administration, the dose is determined individually and depends on the patient’s age and the dosage form used.
Recommended dose for children under 2 years of age (only after consultation with a doctor): 20 drops 2 times a day.
Children 2-5 years old: 40 drops 2 times a day.
Drops can be mixed with juice, milk or water.
Contraindications:
Hypersensitivity to ambroxol or auxiliary components of the drugs; 1st trimester of pregnancy; lactation period (breastfeeding).
Precautions:
Ambroxol should not be taken simultaneously with antitussives that can inhibit the cough reflex, such as codeine, as this can make it difficult to remove liquefied mucus from the bronchi.
Ambroxol should be used with caution in patients with a weakened cough reflex or impaired mucociliary transport due to the possibility of sputum accumulation.
Patients taking ambroxol are not recommended to perform breathing exercises due to difficulty in expectorating sputum. In patients in severe condition, aspiration of liquefied sputum should be performed.
Ambroxol should not be taken immediately before bedtime.
In patients with bronchial asthma, ambroxol may increase cough.
Side effects:
Allergic reactions: rare – skin rash, urticaria, exanthema, facial swelling, shortness of breath, itching, fever; frequency unknown – anaphylactic reactions, including anaphylactic shock, angioedema, skin itching, allergic contact dermatitis.
From the digestive system: often – nausea; uncommon – vomiting, diarrhea, dyspepsia, abdominal pain.
From the nervous system: often – dysgeusia.
From the skin and subcutaneous tissues: very rare – toxic epidermal necrolysis (Lyell’s syndrome), Stevens-Johnson syndrome; frequency unknown – acute generalized eczematous pustulosis.
From the respiratory system: often – decreased sensitivity in the oral cavity or pharynx; rarely – dryness of the mucous membrane of the respiratory tract, rhinorrhea; in isolated cases – dryness of the mucous membrane of the pharynx.
Storage method:
Store at temperatures not exceeding 30 degrees.
Package:
The cardboard box contains a 15 ml bottle and paper instructions.
