Description
Trade name:
Urivin
Compound:
Each sachet contains:
Piperazine citrate 165 mg
Colchicine 0.3 mg
Kellin 1.75 mg
Atropine sulfate 0.128 mg.
Auxiliary components:
Sodium bicarbonate, anhydrous citric acid, povidone, PV P, lemon oil, sucrose.
Properties:
Piperazine has been known for many years as an effective drug in the treatment of gout and urinary tract lithiasis. It increases the solubility of urates in urine. Toxicity is low. Colchicine provides rapid pain relief in acute attacks of gout. The drug is specific for this condition and can thus be used as a diagnostic tool in gout and gouty arthritis. Colchicine has anti-inflammatory properties. Although it is very effective in the treatment of acute gouty arthritis, it is not effective in other types of pain. It is not an analgesic and does not affect uric acid clearance. Instead, colchicine binds to the microtubule proteins of neutrophils. This binding, in turn, inhibits the migration of neutrophils to the site of inflammation, thereby interfering with the inflammatory response to urate crystal deposition.
Kellin has an antispasmodic effect on smooth muscles. Atropine sulfate is also added to relieve spasm of the urinary tract.
Indications:
Acute and chronic gout.
Gouty arthritis.
For the prevention of urolithiasis.
Method of administration and dosage:
For an acute attack: dissolve 1 sachet in half a glass of water and take orally 6 times a day.
To prevent an acute attack: dissolve 2 sachets in a glass of water and take 2 times a day.
As a preventative measure: dissolve 2 sachets in a glass of water and take once a day.
Contraindications:
Known hypersensitivity to any of the components of the drug.
Blood dyscrasia.
Acute dehydration, anuria or hyperkalemia.
Precautions:
Use with caution in patients with serious gastrointestinal, renal, hepatic and cardiovascular disorders.
The drug should not be used in children, elderly, weakened patients and lactating women.
Side effects:
Nausea, vomiting, abdominal pain and diarrhea may occasionally occur.
Storage method:
At a temperature not exceeding 30 degrees. In a dry place.
Package:
The cardboard box contains 10 sachets and paper instructions.
