Description
Trade name:
Urosolvine
Compound:
Each sachet contains:
Piperazine citrate 0.1408 g (up to 0.128 g piperazine hydrate).
Colchicine 0.3 mg.
Atropine sulfate 0.128 mg.
Auxiliary components:
Sodium bicarbonate, anhydrous citric acid, tartaric acid, PV P, lemon oil, sucrose.
Properties:
Piperazine has been known for many years as an effective drug in the treatment of gout and urinary tract lithiasis.
It increases the solubility of urates in urine and has low toxicity.
Colchicine provides rapid pain relief in acute attacks of gout, and the drug is specific for this condition, so it can be used as a diagnostic tool for gout and gouty arthritis. Colchicine has anti-inflammatory properties. Although it is very effective in the treatment of acute gouty arthritis, it is not effective for other types of pain. It is not an analgesic and does not affect uric acid clearance. Instead, colchicine binds to the microtubule proteins of neutrophils. This binding, in turn, inhibits the migration of neutrophils to the site of inflammation, thereby interfering with the inflammatory response to urate crystal deposition.
Atropine sulfate is added to relieve urinary tract spasm.
Indications:
Acute and chronic gout.
Gouty arthritis.
For the prevention of urolithiasis.
Method of administration and dosage:
For an acute attack: dissolve 1 sachet in half a glass of water and take 6 times a day.
To prevent an acute attack: dissolve 2 sachets in a glass of water and take 2 times a day.
As a preventative measure: dissolve 2 sachets in a glass of water and take once a day.
Contraindications:
Known hypersensitivity to any of the components of the drug.
Blood dyscrasia.
Acute dehydration, anuria or hyperkalemia.
Precautions:
Use with caution in patients with serious gastrointestinal, renal, hepatic and cardiovascular disorders.
The drug should not be taken by children, geriatrics, debilitated patients and lactating women.
Side effects:
Nausea, vomiting, abdominal pain and diarrhea may occasionally occur.
Storage method:
At a temperature not exceeding 25 degrees. In a dry place.
Package:
The cardboard box contains 12 sachets and paper instructions.
