Description
Trade name:
Otrivin
Compound:
1 ml of solution contains:
Xylometazoline hydrochloride 0.05 mg.
Properties:
Xylometazoline has an alpha-adrenergic effect: it causes narrowing of blood vessels of the nasal mucosa, eliminating swelling and hyperemia of the nasopharyngeal mucosa. Xylometazoline also reduces concomitant hypersecretion of mucus and facilitates drainage of nasal passages blocked by secretions, thus improving nasal breathing in case of nasal congestion. Otrivin is well tolerated by patients with sensitive mucous membranes, its effect does not interfere with mucus secretion.
In therapeutic concentrations, the drug does not irritate the mucous membrane and does not cause hyperemia.
The effect begins within a few minutes after application and lasts for 12 hours.
Indications:
– Acute respiratory diseases with rhinitis;
– Acute allergic rhinitis;
– Hay fever;
– Sinusitis;
– Eustachitis;
– Otitis media (to reduce swelling of the nasopharyngeal mucosa);
– Preparation of the patient for diagnostic manipulations in the nasal passages, including rhinoscopy.
Method of administration and dosage:
Intranasally.
Children aged 1-2 years should use only as directed by a doctor.
Children aged 2-11 years: 1-2 drops in each nostril 1-2 times a day. The maximum frequency of use is 3 times a day.
Contraindications:
– Hypersensitivity to xylometazoline and other components of the drug;
– Arterial hypertension;
– Tachycardia;
– Severe atherosclerosis;
– Glaucoma;
– Dry rhinitis or atrophic rhinitis;
– Hyperthyroidism;
– Condition after transsphenoidal hypophysectomy;
– Surgical interventions on the meninges (in history);
– Children under 1 year of age for Otrivin 0.05%.
Precautions:
With caution: diabetes mellitus; pheochromocytoma; cardiovascular diseases (including coronary heart disease, angina); prostatic hyperplasia; with increased sensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.
Use during pregnancy and breastfeeding: The drug should not be used during pregnancy.
During lactation, use is possible only under the supervision of a physician and after careful assessment of the risk-benefit ratio for the mother and fetus. Do not exceed the recommended dose.
It is not recommended to use continuously for more than 10 days, as prolonged or excessive use of the drug may cause a rebound effect (drug-induced rhinitis) and/or atrophy of the nasal mucosa.
Side effects:
From the immune system: very rare – hypersensitivity reactions (angioedema, rash, itching).
From the nervous system: often – headache; rarely – insomnia, depression (with prolonged use in high doses).
From the sensory organs: very rarely – impaired clarity of visual perception.
From the cardiovascular system: rarely – sensation of palpitations, increased blood pressure; very rarely – tachycardia, arrhythmia.
From the respiratory system: often – irritation and/or dryness of the nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion of the nasopharyngeal mucosa.
From the digestive system: often – nausea; rarely – vomiting.
Local reactions: often – burning at the site of application.
If any of the above side effects worsen, or the patient notices any other side effects, he should inform the doctor.
Storage method:
Keep out of reach of children at a temperature not exceeding 25 degrees.
Package:
The cardboard box contains a 15 ml bottle and paper instructions.








