Description
Trade name:
Zithromax 22.5 ml/900 mg powder for suspension.
Composition:
Each 5 ml of the finished suspension contains:
Azithromycin 200 mg.
Excipients:
Trisodium phosphate, sucrose, hydroxypropyl cellulose, flavoring.
Properties:
Bacteriostatic antibiotic from the macrolide-azalide group. Has a broad spectrum of antibacterial action.
Indications:
-infections of the upper respiratory tract and ENT organs (pharyngitis/tonsillitis, sinusitis, otitis media);
-infections of the lower respiratory tract (acute bronchitis, exacerbation of chronic bronchitis, pneumonia, including those caused by atypical pathogens);
– skin and soft tissue infections (erysipelas, impetigo, secondarily infected dermatoses).
– the initial stage of Lyme disease (borreliosis) – erythema migrans.
Method of administration and dosage:
The suspension is administered orally once a day, 1 hour before or 2 hours after meals. After taking the drug, the child must be offered to drink a few sips of water so that he can swallow the rest of the suspension.
For infections of the upper and lower respiratory tract, ENT organs, skin and soft tissues, the drug is prescribed at a rate of 10 mg / kg of body weight 1 time / day for 3 days, the course dose is 30 mg / kg.
For Lyme disease (the initial stage of borreliosis) – erythema migrans, it is prescribed on the 1st day at a dose of 20 mg / kg 1 time / day, then from the 2nd to 5th day – at the rate of 10 mg/kg 1 time/day. Course dose – 60 mg/kg
Contraindications:
-Hypersensitivity to azithromycin (including other macrolides) or other components of the drug;
-severe renal failure (creatinine clearance (CC) less than 40 ml/min);
-severe hepatic failure (Child-Pugh class C);
-simultaneous administration with ergotamine and dihydroergotamine;
-children under 6 months;
-deficiency of sucrase/isomaltase, fructose intolerance, glucose-galactose malabsorption;
-hypersensitivity to erythromycin; ketolidam.
Precautions:
If you miss an antibiotic dose, take the missed dose as soon as possible and take subsequent doses at 24-hour intervals.
For children weighing less than 15 kg, it is necessary to measure the calculated dose especially carefully.
Side effects:
From the digestive system: nausea, vomiting, diarrhea, abdominal pain, loose stools, flatulence, indigestion, anorexia, constipation, change in tongue color, pseudomembranous colitis, cholestatic jaundice, hepatitis, changes in laboratory parameters of liver function, liver failure, liver necrosis (possibly fatal).
Allergic reactions: itching, skin rash, angioedema, urticaria, photosensitivity, anaphylactic reaction (in rare cases fatal), erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.
From the cardiovascular system: palpitations, arrhythmia, ventricular tachycardia, prolongation of the QT interval, torsades de pointes.
From the nervous system: dizziness/vertigo, headache, seizures, drowsiness, paresthesia, asthenia, insomnia, hyperactivity, aggressiveness, anxiety, nervousness.
From the sensory organs: tinnitus, reversible hearing impairment up to deafness (when taking high doses for a long time), impaired perception of taste and smell.
From the circulatory and lymphatic systems: thrombocytopenia, neutropenia, eosinophilia.
From the musculoskeletal system: arthralgia.
From the genitourinary system: interstitial nephritis, acute renal failure.
Others: vaginitis, candidiasis.
Storage method:
Store at a temperature not exceeding 25 degrees, after dilution, the drug should be stored for no more than 5 days at the same temperature.
Packaging:
The cardboard box contains paper instructions, a plastic bottle with the drug, a plastic bottle with sterile water for dilution and a measuring syringe.
