Description
Trade name:
Viagra
Compound:
Each tablet contains:
Sildenafil 50 mg.
Auxiliary components:
Mannitol, crospovidone, polyvinyl acetate, povidone, croscarmellose sodium, microcrystalline cellulose, colloidal silicon dioxide, sucralose, indigo carmine.
Properties:
The physiological mechanism of erection is associated with the release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. This, in turn, leads to an increase in cGMP levels, subsequent relaxation of the smooth muscle tissue of the corpus cavernosum and increased blood flow.
Sildenafil does not have a direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of NO by inhibiting PDE5, which is responsible for the breakdown of cGMP.
A prerequisite for the effectiveness of sildenafil is sexual stimulation. Sildenafil restores impaired erectile function under conditions of sexual stimulation by increasing blood flow to the cavernous bodies of the penis.
Indications:
Treatment of erectile dysfunction characterized by the inability to achieve or maintain an erection of the penis sufficient for satisfactory sexual intercourse. Sildenafil is effective only with sexual stimulation.
Method of administration and dosage:
The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a specific drug with the indications for use and dosage regimen.
Treatment of erectile dysfunction: taken orally approximately 1 hour before planned sexual activity. A single dose is 50 mg. Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. The maximum single dose is 100 mg. The maximum frequency of administration is 1 time per day. For elderly patients over 65 years of age and with concomitant renal or hepatic dysfunction, the dose is 25 mg.
Contraindications:
Concomitant use of nitric oxide donors or nitrates in any form, hypersensitivity to sildenafil.
Precautions:
Before starting to take sildenafil for the treatment of erectile dysfunction, a cardiovascular examination should be performed.
Use with caution in patients with a tendency to bleeding, gastric ulcer and duodenal ulcer in the acute phase, and hereditary retinitis pigmentosa.
Sildenafil is not used in patients under 18 years of age.
Side effects:
From the central nervous system: headache, hot flashes, dizziness, insomnia are possible.
From the digestive system: dyspepsia, asthenia, diarrhea, abdominal pain, nausea are possible.
Storage method:
Store in a cool, dry place at a temperature not exceeding 30 degrees.
