Description
Trade name:
Tobrin
Compound:
Each ml contains:
Tobramycin 3 mg
Auxiliary components:
benzalkonium chloride, disodium edetate dihydrate, sodium chloride, hypromellose, water d/i.
Properties:
An antibiotic of the aminoglycoside group with a broad spectrum of action. It has a bactericidal effect, disrupting protein synthesis and the permeability of the cytoplasmic membrane of bacteria.
Highly active against Pseudomonas aeruginosa.
Tobramycin is active against gram-negative bacteria: Escherichia coli, Proteus spp. (indole-positive and indole-negative strains), Klebsiella spp., Serratia spp., Providencia spp., Enterobacter spp., Shigella spp., Salmonella spp., Citrobacter spp., Haemophilus influenzae; gram-positive bacteria: Staphylococcus spp. (including strains producing penicillinase).
Inactive against Streptococcus spp. (including Enterococcus spp.).
Indications:
For local use: eye infections (as part of combination therapy). And severe infectious and inflammatory diseases caused by pathogens sensitive to tobramycin.
Method of administration and dosage:
The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a specific drug with the indications for use and dosage regimen.
Individual, depending on the indications, severity of the disease, age of the patient.
The average dose for adults is 1-2 drops in each eye every 4 hours.
Contraindications:
Hypersensitivity to tobramycin and other aminoglycosides.
Precautions:
Systemic use of tobramycin is possible when the expected benefit of treatment outweighs the risk of developing side effects in the following cases: in patients with impaired renal function, hearing, myasthenia and parkinsonism.
Side effects:
From the central nervous system and peripheral nervous system: ototoxic effect, headache, lethargy, disorientation, impaired neuromuscular transmission.
From the digestive system: nausea, vomiting, increased levels of liver transaminases and bilirubin in the blood.
From the hematopoietic system: anemia, granulocytopenia, thrombocytopenia.
From the side of metabolism: hypocalcemia, hyponatremia, hypokalemia, hypomagnesemia.
Others: possible nephrotoxic effect, allergic reactions.
Storage method:
Store at temperatures not exceeding 30 degrees.
Once opened, do not use for more than 28 days.
Package:
The cardboard box contains a 5 ml dropper bottle and paper instructions.
