Description
Trade name:
Rani-F
Compound:
Each sachet contains:
Famotidine 20 mg
Auxiliary components:
Anhydrous citric acid, sodium bicarbonate, sodium saccharin, mannitol, tutti-frutti flavoring.
Properties:
Famotidine is a competitive histamine antagonist. By acting on histamine H2 receptors of parietal cells, it significantly reduces the secretion of hydrochloric acid caused by various irritants. Basal secretion of hydrochloric acid is also reduced. The evoked secretion of pepsinogen is inhibited to a lesser extent. It causes a dose-dependent suppression of hydrochloric acid production and a decrease in pepsin activity. It does not significantly change the level of gastrin in plasma.
Indications:
Benign gastric ulcer.
Peptic ulcer of the duodenum (treatment and prevention of relapses).
Hypersecretory conditions such as Zollinger-Ellison syndrome.
Treatment of gastroesophageal reflux disease (reflux esophagitis).
Prevention of the development of symptoms and erosions or ulceration associated with gastroesophageal reflux disease.
Method of administration and dosage:
Famotidine is most effective in the evening before bedtime. When taking famotidine twice daily, one dose should be taken in the morning and the other in the evening before bedtime.
Dissolve the contents of the sachet in a glass of water and take orally.
Contraindications:
Hypersensitivity to the active substance, other H2-receptor antagonists or other components of the drug.
Age, period of pregnancy and breastfeeding (due to lack of necessary clinical experience).
Precautions:
Before starting treatment, it is necessary to exclude the possibility of malignant disease of the esophagus, stomach or duodenum, since Famotidine can mask symptoms.
Side effects:
From the digestive system: dry mouth, nausea, vomiting, abdominal pain, flatulence, constipation, diarrhea, loss of appetite; increased activity of liver enzymes, hepatitis, acute pancreatitis.
From the central nervous system: headache, dizziness, insomnia, anxiety, tinnitus; increased fatigue, drowsiness, depression, nervousness, psychosis; blurred vision, accommodation paresis; confusion, hallucinations, hyperthermia.
From the cardiovascular system: bradycardia, arrhythmia, vasculitis, decreased blood pressure, atrioventricular block.
Dermatological reactions: dry skin, alopecia, acne vulgaris, skin rash, itching, bronchospasm,
angioedema, anaphylactic shock, other manifestations of hypersensitivity.
From the hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, hypoplasia, aplasia of the bone marrow.
From the reproductive system: with prolonged use of large doses – hyperprolactinemia, gynecomastia, amenorrhea,
decreased libido, impotence.
Storage method:
Store at temperatures not exceeding 30 degrees.
Package:
The cardboard box contains 6 sachets and paper instructions.
