Description
Tradename:
Philozac
Compound:
Each capsule contains:
fluoxetine hydrochloride 23.6 mg, equivalent to 20 mg fluoxetine.
Properties:
An antidepressant from the group of selective serotonin reuptake inhibitors. It has a thymoanaleptic and stimulating effect.
Effective for endogenous depression and obsessive-compulsive disorders. A lasting clinical effect occurs after 1-2 weeks of treatment.
Indications:
– depression of various origins;
– obsessive-compulsive disorders;
-bulimic neurosis.
Directions for use and dosage:
The drug is taken orally, at any time, regardless of meals.
Depressive state
The initial dose is 20 mg 1 time / day in the first half of the day, regardless of meals. If necessary, the dose can be increased to 40-60 mg/day, divided into 2-3 doses (by 20 mg/day weekly). The maximum daily dose is 80 mg in 2-3 doses.
The clinical effect develops 1-2 weeks after the start of treatment; in some patients it may be achieved later.
Obsessive-compulsive disorders:
The recommended dose is 20-60 mg/day.
Bulimic neurosis:
The drug is used in a daily dose of 60 mg, divided into 2-3 doses.
Contraindications:
-simultaneous use with MAO inhibitors (and within 14 days after their discontinuation);
-simultaneous use of thioridazine (and for 5 weeks after discontinuation of fluoxetine), pimozide;
-pregnancy and breastfeeding period;
severe renal dysfunction (creatinine clearance less than 10 ml/min);
-liver failure;
– lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
– age up to 18 years;
– increased sensitivity to the drug
Precautionary measures:
With depression, there is a possibility of suicide attempts, which may persist until stable remission occurs.
Careful monitoring of patients at risk is necessary. Clinicians should encourage patients to promptly report any distressing thoughts or feelings.
feelings that cause anxiety.
Epileptic seizures: Floxetine should be prescribed with caution to patients who have had epileptic seizures.
Diabetes mellitus: glycemic control in diabetic patients during treatment with fluoxetine showed hypoglycemia; after discontinuation of the drug, hyperglycemia developed. Insulin dosage adjustments may be required at the start or after treatment with fluoxetine.
In patients with severe liver dysfunction, it is recommended to prescribe lower doses of fluoxetine, or prescribe the drug every other day.
Side effects:
Atrial flutter, hot flashes, nausea, diarrhea, loss of appetite, headache, impaired attention, insomnia, unusual dreams, hyperhidrosis, itching, polymorphic skin rash, urticaria, frequent urination, impaired ejaculation, gynecological bleeding.
Storage method:
Store at temperatures from 15 to 30 degrees.
