Description
Trade name:
Megafen N
Compound:
Each 5 ml of suspension contains:
Ibuprofen 100 mg
Auxiliary components:
Sucrose, methylparaben, propylparaben, sodium benzoate, kaolin, citric acid anhydride, sodium dihydrate, simethicone emulsion 30%, agar, sorbitol solution 70% polysorbate 80, vanillin, orange oil, aerosil 200, purified water.
Properties:
NSAID. Has antipyretic, analgesic and anti-inflammatory effects.
The antipyretic effect is due to the blocking of COX-1 and COX-2 in the arachidonic acid cascade of the central nervous system, which leads to a decrease in the synthesis of prostaglandins, a decrease in their concentration in the cerebrospinal fluid and a decrease in the excitation of the thermoregulation center. The effect of lowering the temperature during fever begins 30 minutes after taking the drug, its maximum effect appears after 3 hours.
Indications:
The drug is intended for the treatment of children only.
Elevated body temperature of various origins with:
colds;
ARVI, including influenza;
sore throat (tonsillitis);
childhood infections;
post-vaccination reactions.
Pain syndrome of various origins of weak and moderate intensity with:
toothache, painful teething;
ear pain due to inflammation of the middle ear;
headache, migraine;
neuralgia;
pain in muscles and joints due to injuries to the musculoskeletal system.
It is intended for symptomatic therapy, reduction of pain and inflammation during the period of use, and does not affect the progression of the disease.
Method of administration and dosage:
The drug is taken orally, after meals. Before use, shake the bottle until a homogeneous suspension is obtained.
Children 3-6 months: 2.5 ml 3 times a day.
Children 6-12 months: 2.5 ml 3 times a day.
Children 1-2 years: 2.5 ml 3-4 times a day.
Children 3-7 years: 5 ml 3-4 times a day.
Children 8-12 years: 10 ml 3-4 times a day.
Taking the drug in a single dose can be repeated every 6-8 hours. The maximum daily dose should not be exceeded.
Contraindications:
– hypersensitivity to ibuprofen or other NSAIDs (including acetylsalicylic acid), as well as to the auxiliary components of the drug;
– severe liver failure, active liver disease;
-confirmed hyperkalemia;
-inflammatory bowel diseases;
-sucrase/isomaltase deficiency;
-fructose intolerance, glucose-galactose malabsorption;
– blood clotting disorders (including hemophilia, prolonged bleeding time, tendency to bleeding, hemorrhagic diathesis);
– children under 3 months of age.
Precautions:
In patients with bronchial asthma or other diseases associated with bronchospasm, ibuprofen may increase the risk of developing bronchospasm. The use of the drug in these patients is permissible only under the condition of observing great caution, and in case of breathing difficulties, you should immediately consult a doctor.
During long-term treatment with NSAIDs, it is necessary to monitor the peripheral blood picture and the functional state of the liver and kidneys.
Side effects:
From the digestive system: NSAID-gastropathy (nausea, vomiting, decreased appetite, heartburn, abdominal pain, diarrhea, flatulence, pain and discomfort in the epigastric region); ulceration of the mucous membrane of the gums and the gastrointestinal mucosa (in some cases complicated by perforation and bleeding); dryness of the oral mucosa, aphthous stomatitis, pancreatitis, constipation, hepatitis.
From the respiratory system: shortness of breath, bronchospasm.
From the urinary system: acute renal failure, allergic nephritis, nephrotic syndrome (edema), polyuria, cystitis.
Allergic reactions: skin itching, skin rash (erythematous or urticaria), angioedema, anaphylactoid reactions, anaphylactic shock, bronchospasm, fever, erythema multiforme exudative (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell’s syndrome), eosinophilia, allergic rhinitis.
Storage method:
In a cool, dry place at a temperature not exceeding 30 degrees.
Package:
The cardboard box contains a 120 ml bottle and paper instructions.
