Description
Trade name:
Macrofuran
Compound:
Each capsule contains:
nitrofurantoin 50 mg
Auxiliary components:
Starch, talc, lactose monohydrate.
Properties:
An antimicrobial agent, a derivative of the nitrofuran group, primarily for the treatment of urinary tract infections. Disrupts protein synthesis in bacteria and cell membrane permeability. Active against gram-positive and gram-negative bacteria (Staphylococcus spp., Streptococcus spp., Shigella dysenteria spp., Shigella flexneri spp., Shigella boydii spp., Shigella sonnei spp., Escherichia coli, Proteus spp.).
Indications:
– bacterial urinary tract infections (pyelitis, pyelonephritis, urethritis, cystitis);
– prevention of infections during urological operations or examinations (cystoscopy, catheterization, etc.).
Method of administration and dosage:
Acute uncomplicated urinary tract infections: 50 mg 4 times daily for 7 days.
Chronic recurrent urinary tract infections: 100 mg 7 times a day for 7 days.
For long-term use: 100 mg once a day.
For prevention, take 50 mg up to 4 times a day during procedures and 3 days after.
Contraindications:
-hypersensitivity;
– chronic renal failure;
– heart failure stage II-III;
-cirrhosis;
– chronic hepatitis;
– deficiency of glucose-6-phosphate dehydrogenase;
– acute porphyria;
-pregnancy;
– lactation period;
-childhood.
Precautions:
The effect of the drug on the performance of potentially dangerous activities that require special attention and quick reactions:
During the treatment period, it is necessary to exercise caution when driving vehicles and engaging in other potentially dangerous activities that require increased concentration and speed of psychomotor reactions (if dizziness and drowsiness occur).
Side effects:
Nausea, vomiting, allergic reactions (lupus-like syndrome, arthralgia, myalgia, anaphylaxis, chills, eosinophilia, rash), dizziness, headache, asthenia, nystagmus, drowsiness, interstitial changes in the lungs, broncho-obstructive syndrome, fever, cough, chest pain, hepatitis, cholestatic syndrome, peripheral neuropathy, pancreatitis, pseudomembranous enterocolitis, rarely – abdominal pain, diarrhea.
Storage method:
Store at temperatures not exceeding 30 degrees.
Package:
The cardboard box contains 3 blisters of 10 capsules and paper instructions.
