Description
Trade name:
Levcet
Composition:
Each tablet contains:
Levocetirizine dihydrochloride 5 mg.
Excipients: microcrystalline cellulose, sodium croscarmellose, pregelatinized starch, colloidal silicon dioxide, magnesium stearate.
Properties:
Levocetirizine is the R-enantiomer of cetirizine; a competitive histamine antagonist; blocks histamine H1 receptors, the affinity for which is 2 times higher than that of cetirizine. Levocetirizine affects the histamine-dependent stage of allergic reactions; reduces the migration of eosinophils, reduces vascular permeability, limits the release of inflammatory mediators. Prevents the development and alleviates the course of allergic reactions, has an anti-exudative, antipruritic effect; has virtually no anticholinergic and antiserotonin effects. In therapeutic doses, it has virtually no sedative effects.
Indications:
Treatment of symptoms of year-round (persistent) and seasonal (intermittent) allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, nasal congestion, rhinorrhea, lacrimation, conjunctival hyperemia;
hay fever;
urticaria;
other allergic dermatoses accompanied by itching and rashes.
Method of administration and dosage:
The drug is taken orally during meals or on an empty stomach, without chewing, with a small amount of water. It is recommended to take the daily dose in 1 dose.
Adults and children over 6 years old: the daily dose is 5 mg. The maximum daily dose is 5 mg.
Children under 6 years of age are not prescribed tablets: a different, liquid dosage form is used for them.
Contraindications:
Hypersensitivity to the active substance, cetirizine, hydroxyzine, any piperazine derivative or to any other excipient of the drug; lactase deficiency, lactose intolerance, glucose-galactose malabsorption; end-stage renal failure, children under 6 years of age (for tablets, due to limited data on efficacy and safety).
With caution:
Caution is required in the following conditions: chronic renal failure (dosage adjustment is necessary); in elderly patients (with age-related decrease in glomerular filtration), with simultaneous use with alcohol, prostatic hyperplasia, as well as in the presence of other predisposing factors to urinary retention, since levocetirizine may increase the risk of urinary retention; when prescribed to pregnant women and during breastfeeding.
Precautions:
Levocetirizine may cause increased drowsiness, therefore, the drug may affect the ability to drive a car or operate machinery. During the period of taking Levocetirizine, it is advisable to refrain from performing potentially dangerous types of work that require increased concentration and speed of psychomotor reactions (including driving a car and operating machinery).
Side effects:
From the immune system: hypersensitivity reactions, including anaphylaxis.
From the metabolism: increased appetite.
From the psyche: anxiety, aggression, agitation, depression, hallucinations, insomnia, suicidal thoughts.
From the nervous system: convulsions, thrombosis of the sinuses of the dura mater, paresthesia, dizziness, fainting, tremor, dysgeusia.
From the organ of hearing: vertigo.
From the visual system: visual impairment, blurred vision, inflammatory manifestations.
From the cardiovascular system: angina pectoris, tachycardia, palpitations, jugular vein thrombosis.
From the respiratory system: dyspnea, increased rhinitis symptoms.
From the digestive system: nausea, vomiting, diarrhea.
Hepatobiliary disorders: hepatitis, changes in liver function tests.
From the urinary system: dysuria, urinary retention.
From the skin and soft tissues: angioedema, persistent drug erythema, itching, rash, urticaria, hypotrichosis, cracks, photosensitivity.
From the musculoskeletal system: muscle pain, arthralgia.
General disorders: peripheral edema, weight gain.
Other: cross-reactivity.
If any of the side effects listed in the instructions worsen, or you notice any other side effects not listed in the instructions, tell your doctor.
Storage method:
Keep out of reach of children, in a dark place, at a temperature not exceeding 25 degrees.
Packaging:
A cardboard box contains 2 blisters of 10 tablets, paper instructions.
