Description
Trade name:
Flurest N
Compound:
Each tablet contains:
Paracetamol 500 mg
Phenylephrine hydrochloride 5 mg
Chlorphenamine maleate 2 mg.
Auxiliary components:
Starch, povidone, sodium sorbitol, sodium lauryl sulfate, microcrystalline cellulose, talc.
Properties:
A combination drug that has antipyretic, analgesic, alpha-adrenergic, vasoconstrictor and antihistamine effects, eliminates cold symptoms.
Paracetamol is a non-narcotic analgesic; it blocks COX, mainly in the central nervous system, affecting the pain and thermoregulation centers; it has an analgesic and antipyretic effect.
Phenylephrine is an alpha-adrenergic agonist with moderate vasoconstrictive action.
Chlorphenamine is an H1-histamine receptor blocker. It constricts nasal blood vessels, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses; reduces exudative manifestations, suppresses symptoms of allergic rhinitis.
Indications:
Symptomatic treatment of acute respiratory infections, acute respiratory viral infections (including influenza), accompanied by fever, pain syndrome, rhinorrhea.
Method of administration and dosage:
Adults and children over 12 years old:
1-2 tablets every 6 hours. Maximum daily dose is 8 tablets.
The course of treatment is no longer than 7 days.
Contraindications:
Diabetes mellitus (severe); concomitant use of tricyclic antidepressants, MAO inhibitors, beta-blockers; pregnancy; lactation period; children under 12 years of age; hypersensitivity to the components of the combination.
With caution:
Pheochromocytoma, diabetes mellitus, bronchial asthma, COPD, glucose-6-phosphate dehydrogenase deficiency, blood diseases, congenital hyperbilirubinemia (Gilbert’s syndrome, Dubin-Johnson syndrome, Rotor syndrome), liver and/or kidney failure, closed-angle glaucoma, prostatic hyperplasia.
Precautions:
During the treatment period, you should not take sleeping pills or anxiolytic drugs (tranquilizers).
Do not take with other medications containing paracetamol.
If symptoms do not go away within 5 days, you should consult a doctor.
During the treatment period, it is necessary to refrain from drinking ethanol (hepatotoxic effects may develop).
Side effects:
Allergic reactions: skin rash, itching, urticaria, angioedema.
From the central nervous system: dizziness, difficulty falling asleep, increased excitability.
From the cardiovascular system: increased blood pressure, tachycardia.
From the digestive system: dry mouth, nausea, vomiting, epigastric pain, hepatotoxic effect.
From the organ of vision: mydriasis, paresis of accommodation, increased intraocular pressure.
From the hematopoietic system: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.
From the urinary system: renal colic, glucosuria, inertial nephritis, papillary necrosis.
From the respiratory system: broncho-obstruction.
Storage method:
At a temperature not exceeding 30 degrees.
Package:
The cardboard box contains 2 blisters of 10 tablets and paper instructions.
