Description
Trade name:
Gynozol
Compound:
Each gram of cream contains:
Miconazole nitrate 20 mg
Auxiliary components:
Disodium edetate, liquid paraffin, polysorbate 60, propylene glycol, purified water.
Properties:
Miconazole is a synthetic antifungal agent, an imidazole derivative. It has antifungal and antibacterial effects.
The most sensitive to miconazole are dermatomycetes and yeasts. It is active against the causative agent of pityriasis versicolor (Malassezia furfur), causative agents of some dermatomycoses (Candida albicans, Trichophyton, Epidermophyton floccosum, Microsporum). It is active against Dimorphons fungi, Cryptococcus neoformans, Aspergillus spp., Pityrosporum, Torulopsis glabrata, Pseudallescheria boydii; some gram-positive microorganisms, including staphylococci and streptococci. The fungicidal and fungistatic effect of miconazole nitrate is due to the inhibition of ergosterol biosynthesis, changes in the lipid composition and permeability of the cell wall, which causes the death of the fungal cell.
Indications:
Method of administration and dosage:
Adults: one applicator into the vagina once a day, in the evening before bedtime for 10-14 days, or one applicator in the morning and evening for 7 days.
Treatment continues for several days after the symptoms of the disease disappear.
Contraindications:
Precautions:
Do not interrupt treatment during the menstrual cycle.
Simultaneous treatment of the sexual partner is necessary.
The appearance of local allergic reactions or the absence of clinical improvement within 7 days requires discontinuation of treatment and further examination.
Pregnancy and lactation period:
Miconazole should be used during pregnancy only if the potential benefit to the mother outweighs the possible risk to the fetus.
