Description
Trade name:
Pantoloc
Compound:
Each tablet contains:
Pantoprazole 20 mg
Auxiliary components:
Sodium carbonate,
Mannitol (E421)
Crospovidone
Povidone K90
Calcium stearate.
Properties:
Pantoprazole is a substituted benzimidazole that inhibits gastric hydrochloric acid secretion by specific blockade of the proton pump of the parietal cells. Pantoprazole is converted to its active form, a cyclic sulfenamide, in the acidic environment of the parietal cells, where it inhibits the enzyme H+, K+-ATPase, i.e. the final stage of hydrochloric acid formation in the stomach.
Indications:
Gastroesophageal reflux disease, reflux esophagitis; Helicobacter pylori eradication (as part of complex therapy); duodenal ulcer; gastric ulcer; Zollinger-Ellison syndrome and other pathological hypersecretory diseases.
Method of administration and dosage:
Orally, before meals (usually before breakfast), with the required amount of water. Tablets should be swallowed whole, without chewing.
The doctor selects the dose depending on the diagnosis.
Adults and adolescents aged 12 years and over: 1 tablet of pantoprazole per day. In individual cases, the dose can be increased to 2 tablets of pantoprazole per day. Usually 4 weeks of treatment are required. If necessary, the duration of treatment is increased to 8 weeks.
Children under 12 years of age: Pantoprazole is not recommended for use in children under 12 years of age due to limited safety and efficacy data in this age group.
Contraindications:
Hypersensitivity to pantoprazole, benzimidazole derivatives or other components of the drug. Concomitant use of atazanavir. Due to insufficient data, the use of pantoprazole for the treatment of children under 12 years of age is not recommended.
Precautions:
In the presence of any alarming symptom (e.g. significant weight loss, recurrent vomiting, dysphagia, hematemesis, anaemia, melena) and in the presence or suspicion of gastric ulcer, malignancy should be excluded, since treatment with pantoprazole may alleviate symptoms and delay diagnosis.
The need for further investigation should be considered if symptoms persist despite adequate therapy.
Side effects:
Approximately 5% of patients may experience side effects of the drug. The most common side effects are diarrhea and headache, which occur in approximately 1% of patients.
From the nervous system and sensory organs: uncommon – headache, dizziness, sleep disturbance. Rare – visual acuity disturbance, depression (and aggravation). Very rare – disorientation, paresthesia. Frequency unknown – hallucinations, confusion (especially in predisposed patients, as well as exacerbation of these symptoms if they were present previously).
From the gastrointestinal tract: often – gastric polyps (benign). Uncommon – diarrhea, nausea/vomiting, bloating and flatulence, constipation, dry mouth, abdominal pain and discomfort.
Storage method:
In a cool, dry place at a temperature not exceeding 25 degrees
Package:
The cardboard box contains 2 blisters of 7 tablets each and paper instructions.
