Description

Trade name:

Antodine

Compound:

Each tablet contains:
Famotidine 20 mg.

Properties:

Famotidine is a competitive histamine H2 receptor inhibitor. It works by reducing the amount of acid produced by the stomach.

Indications:

Treatment and prevention of stomach and intestinal ulcers. Conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.

Gastroesophageal reflux disease (GERD) and other conditions in which acid flows from the esophagus into the stomach, causing heartburn.

Method of administration and dosage:

For heartburn, dyspepsia and gastrointestinal disorders – 1 tablet as needed, when symptoms occur or 30-60 minutes before meals; no more than 2 tablets per day. If symptoms persist for 5 days or if symptoms recur within 2 weeks after the end of the course, a clinical trial is required.

Duodenal ulcer: Initial therapy: The recommended dose is 2 tablets (40 mg) per day at night. Treatment should last 4-8 weeks, but the duration may be shortened if the ulcer has healed. Maintenance therapy: To prevent recurrence of duodenal ulcer, it is recommended to carry out treatment with 1 tablet (20 mg) per day at night. Duration – 12 months.

Benign gastric ulcer: the recommended dose is 2 tablets (40 mg) per day at night. Treatment is carried out for 4-8 weeks.

Zollinger-Ellison syndrome: should be started with a dose of 20 mg at 6 o’clock. The dosage should be adapted to the individual patient and should have the same number of indications.

GERD; erosions or ulcerations of the esophagus; prevention of relapses, erosions or ulcerations: the recommended dose is 20 mg twice a day.

In patients with moderate and renal insufficiency, the dose can be reduced to half or the dosing interval can be increased to 36-48 hours.

Contraindications:

Childhood; hypersensitivity to any component of the drug; pregnancy and lactation.

Precautions:

Before starting Antodin therapy, malignant neoplasms of the stomach must be excluded. Famotidine does not exclude the presence of a malignant tumor of the stomach. No dose adjustment is required in the elderly.

Side effects:

Headache, constipation or diarrhea; difficulty breathing; swelling of the face, lips, tongue or throat; palpitations with severe dizziness; unexplained muscle pain, weakness, fever, abnormal fatigue, dark urine.