Description
Trade name:
Octozinc
Compound:
Each capsule contains:
Zinc sulfate 110 mg (equivalent to 25 mg zinc)
Properties:
Zinc is one of the most important microelements involved in intracellular metabolism and one of the main factors stabilizing cell membranes. It is part of many enzyme systems that regulate the main metabolic processes, and in particular, it is involved in protein synthesis and carbohydrate metabolism.
Indications:
Diseases associated with zinc deficiency in the body, as well as as part of complex therapy for diseases and conditions leading to the development of zinc deficiency:
-enteropathic acrodermatitis (Acrodermatitis enteropathica);
-hypogonadism;
– Alopecia areata;
-malignant alopecia (Alopecia maligna);
-purulent and phlegmonous acne (Acnepustulosa and acne phlegmonosa);
– during long-term treatment with corticosteroids, especially at the time of drug withdrawal;
– as an adjuvant treatment for difficult-to-heal wounds.
Method of administration and dosage:
1-2 capsules per day.
Contraindications:
-hypersensitivity to the active substance or to any of the components of the drug;
– children’s age (up to 4 years).
Precautions:
When using zinc preparations, the risk of copper deficiency should be taken into account (when taking Ostozinc for more than 3-4 months, it is advisable to additionally prescribe copper preparations).
Chronic high dose zinc intake may result in secondary copper deficiency. Symptoms include hypocuprimia, impaired iron mobilization, anemia, leukopenia, neutropenia, decreased superoxide dismutase (SOD) activity, particularly erythrocyte superoxide dismutase (ESOD), decreased ceruloplasmin levels, decreased cytochrome C oxidase activity, increased plasma cholesterol levels, increased low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio, decreased glucose clearance, decreased methionine and leucine enkephalin levels, impaired cardiac function, and impaired pancreatic enzyme activity, amylase, and lipase.
Side effects:
From the digestive system:
– dyspepsia, abdominal pain, nausea, vomiting, diarrhea, heartburn, loss of appetite are possible, especially when taking the drug in high doses;
rarely – metallic taste in the mouth.
From the hematopoietic system:
– hematological disorders caused by copper deficiency, including leukopenia (accompanied by fever, chills, sore throat), neutropenia (with the development of ulcers or pain in the mouth and throat), sideroblastic anemia (accompanied by increased fatigue, weakness).
Others:
-decrease in the concentration of copper in blood plasma;
rarely – headache.
From the immune system:
– allergic reactions to the components of the drug, such as itching and skin rashes.
Storage method:
At a temperature not exceeding 30 degrees.