Description
Tradename:
Trittico 100 mg
Compound:
Each tablet contains:
Trazodone hydrochloride 100 mg
Auxiliary components:
Lactose, dibasic calcium phosphate, microcrystalline cellulose, corn starch, magnesium stearate, castor oil, talc.
Properties:
Antidepressant, thiazolopyridine derivative. It also has thymoleptic, anxiolytic, sedative and muscle relaxant effects. It has a high affinity for certain subtypes of serotonin receptors and inhibits the reuptake of serotonin; the neuronal uptake of norepinephrine and dopamine has little effect.
Indications:
Various forms of depression (endogenous, psychotic, neurotic, somatogenic), incl. with severe anxiety.
Directions for use and dosage:
It is recommended to begin the course of treatment by prescribing the drug in the evening before bedtime with a gradual increase in the dose of the drug by taking it during the day. The course of treatment is at least 1 month. Taking the drug after meals reduces the risk of unwanted effects.
The initial daily dose is 150-200 mg (in 3 divided doses). For mild forms of depression, the average maintenance dose is 150 mg/day; for moderate and severe forms – 300 mg/day. If necessary, the dose can be increased to 600 mg/day. It is recommended to take the bulk of the daily dose before bedtime.
Contraindications:
Ventricular arrhythmia, tachycardia, myocardial infarction (early recovery period), history of priapism, pregnancy, lactation, hypersensitivity to trazodone, age less than 18 years.
Precautionary measures:
Use with caution in case of heart disease, arterial hypotension, arterial hypertension, renal and/or liver failure.
Side effects:
Drowsiness, increased fatigue, dizziness, insomnia, headache, agitation, myalgia, incoordination, paresthesia, disorientation, blackouts, tremor, arrhythmia, conduction disturbances, bradycardia, nausea, vomiting, diarrhea, nasal congestion, priapism.
Storage method:
At a temperature not higher than 30 degrees.