Imigran
August 26, 2024Zithromax
August 26, 2024Arcalion
43.00 EGP
200 mg 40 tablet
Tradename:
Arcalion
Compound:
Each tablet contains:
Sulbutiamine 200 mg
Auxiliary components:
Starch, anhydrous glucose, lactose monohydrate, magnesium stearate, talc, croscarmellose sodium, polysorbitol, povidone, sucrose, aerosil.
Properties:
Sulbutiamine is a parent compound derived from thiamine through a series of structural modifications to the thiamine core:
– formation of a disulfide bond, introduction of a lipophilic ester and opening of the thiazole ring.
Thanks to this modification, sulbutiamine:
is highly soluble in fats, which allows it to be quickly absorbed from the gastrointestinal tract and easily penetrate the BBB;
– the ability to accumulate in the cells of the reticular formation, hippocampus and dentate gyrus, as well as the cells of Purkinje fibers and the glomeruli of the granular layer of the cerebellar cortex, which is confirmed by histochemical analysis.
Placebo-controlled studies in humans, as well as active-controlled studies, have provided evidence of the effectiveness of Arcalion in the symptomatic treatment of functional asthenia.
Sulbutiamine is metabolized to thiamine (vitamin B1). In combination with adenosine triphosphate (ATP), thiamine forms thiamine diphosphate (carboxylase or thiamine pyrophosphate), which as a coenzyme takes part in carbohydrate metabolism.
Indications:
Conditions of overfatigue in adults, accompanied by increased fatigue, decreased performance, and weakness.
Directions for use and dosage:
Inside. Adults only.
Daily dose of the drug: 2-3 tablets (400-600 mg) in 2 divided doses (during breakfast and lunch):
1 tablet with breakfast and 1 tablet with lunch;
or 1 tablet with breakfast and 2 tablets with lunch;
The tablets should be swallowed whole with water.
The duration of treatment should not exceed 4 weeks.
Do not exceed the recommended dose and duration of use.
The patient should be warned that if the condition worsens or does not improve after 4 weeks, consult a doctor.
Contraindications:
– age up to 15 years (due to the appearance of age);
-pregnancy;
– period of breastfeeding;
– lactose deficiency, galactosemia, glucose-galactose malabsorption syndrome, sucrase-isomaltase deficiency, fructose intolerance due to the content of glucose, lactose and sucrose in the preparation as excipients