Description
Trade name:
L-Carnitine 350 mg 20 caps
Compound:
Each capsule contains:
L-Carnitine tartrate – 512.45 mg (equivalent to L-carnitine – 350 mg)
Auxiliary components:
colloidal silicon dioxide, povidone K 25, magnesium stearate.
Properties:
L-carnitine is a natural substance related to B vitamins, necessary for energy metabolism in mammals. Levocarnitine is a means for correcting metabolic processes; it has a metabolic, anabolic, antihypoxic and antithyroid effect, activates fat metabolism, stimulates regeneration, and increases appetite. It is a cofactor of metabolic processes that maintain the activity of coenzyme A (CoA). Reduces basal metabolism, slows down the breakdown of protein and carbohydrate molecules. Promotes penetration through mitochondrial membranes and the breakdown of long-chain fatty acids (palmitic, etc.) with the formation of acetyl-CoA (necessary to ensure the activity of pyruvate carboxylase in the process of gluconeogenesis, the formation of ketone bodies, the synthesis of choline and its esters, oxidative phosphorylation and the formation of ATP). Mobilizes fat (the presence of 3 labile methyl groups) from fat depots. Causes minor CNS depression, increases secretion and enzymatic activity of digestive juices (gastric and intestinal), improves food absorption. Reduces excess body weight and decreases fat content in skeletal muscles. Increases the threshold of resistance to physical activity, reduces the degree of lactate acidosis and restores performance after prolonged physical activity. At the same time, it promotes economical use of glycogen and increases its reserves in the liver and muscles. Has a neurotrophic effect, inhibits apoptosis, limits the area of damage and restores the structure of nervous tissue. Normalizes protein and fat metabolism, increased basal metabolism in thyrotoxicosis (being a partial antagonist of thyroxine); restores the alkaline reserve of the blood.
Indications:
Treatment of primary systemic carnitine deficiency should include, in addition to carnitine, supportive and other therapy as determined by the patient’s condition.
L-carnitine is also indicated for the acute and chronic treatment of patients with inborn errors of metabolism that result in secondary carnitine deficiency.
Improving spermatogenesis.
Directions for use:
L-carnitine capsules are taken orally and should be swallowed whole with a glass of water.
Adults: The recommended dose is 1-3 g/day for a 50 kg person using 350 mg capsules. Clinical response should be monitored.
Contraindications:
Hypersensitivity to levocarnitine or other components in the composition, childhood.
Precautions:
The safety and efficacy of oral levocarnitine in patients with renal insufficiency have not been evaluated. Long-term high-dose oral administration of levocarnitine to patients with severely impaired renal function or to patients with ESRD on dialysis may result in increased concentrations of potentially toxic metabolites. Pregnancy and lactation: not recommended for use during pregnancy and lactation (breastfeeding). If use during lactation is necessary, the issue of discontinuing breastfeeding should be considered.
Side effects:
From the gastrointestinal tract: nausea and vomiting, abdominal cramps and diarrhea.
From the nervous system: myasthenia (only in patients with uremia),
From the skin and integuments: rash, allergic dermatitis.
Storage method:
Store at a temperature not exceeding 30 degrees in a dry place, out of reach of children.
